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  • Title: [Lipid chemical parameters and incidence of genetically determined hyperlipoproteinemias in patients between 20 and 45 years of age with coronary heart disease].
    Author: Wichmann T, Freye HA, Meyer E, Teichmann W, Schmerling S.
    Journal: Z Gesamte Inn Med; 1982 Jun 15; 37(12):379-83. PubMed ID: 7124037.
    Abstract:
    In 35 patients at the age between 20 and 45 years with a manifest coronary heart disease various lipid-chemical parameters were established and compared with a control group of the same age of laboratory-chemically and clinically inconspicuous test persons as well as with a group of patients with infarction older than 45 years. For HDL-cholesterol, LDL-cholesterol as well as LDL significant differences of the mean value were the result in the group of juvenile patients with a coronary heart disease and in the healthy control group as well as the group of older test persons with infarction, which confirm the accumulation of lipid-chemical risk constellations in "juvenile" patient with a coronary heart disease. Moreover, the proportion of primary hyperlipoproteinaemias is essentially greater in these patients than in older test persons with infarction. Apart from the recognition of primary hypercholesterolaemias the diagnostics of autosomally combined hyperlipoproteinaemias is of particular importance.
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