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  • Title: Genetic polymorphism of coagulation factor XIIIB subunit in Japanese.
    Author: Nakamura S, Abe K.
    Journal: Ann Hum Genet; 1982 Jul; 46(3):203-7. PubMed ID: 7125593.
    Abstract:
    Genetic polymorphism of coagulation factor XIIIB subunit in Japanese has been described, using a thin-layer agarose gel isoelectric focusing followed by immunofixation. Phenotypes of factor XIIIB subunit were essentially classified into three common patterns A, B and AB. It is estimated that the phenotypes are determined by two codominant alleles. A new rare variant B' has been detected in Japanese. Gene frequencies calculated from 304 individuals showed FXIII-BA = 0.735, FXIII-BB = 0.252 and FXIII-BB' = 0.013, respectively. The distribution of phenotypes fitted the Hardy-Weinberg equilibrium.
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