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  • Title: [Regulatory characteristics of glycolysis in erythrocytes of sheep].
    Author: Ataullakhanov AI, Ataullakhanov FI, Vitvitskiĭ VM, Zhabotinskiĭ AM, Pichugin AV.
    Journal: Biokhimiia; 1982 Aug; 47(8):1293-8. PubMed ID: 7126696.
    Abstract:
    The regulatory properties of glycolysis in sheep erythrocytes (i. e. dependence of the rate of glucose uptake on ATP concentration) were investigated. A decrease of ATP concentration in the erythrocytes by arsenate causes a sharp rise in the rate of glycolysis, the maximal rate being reached at ATP concentration of about 70% of the original one. Further decrease of ATP lowers the rate of glycolysis; no steady-state rates of energy metabolism are observed within this concentration range. The parameters of glycolysis measured in erythrocytes of various species coincide when the rates of glycolysis are normalized in terms of its maximal value and that of ATP -- in terms of its value at which the maximal rate is reached. The identities of regulatory properties of glycolysis take place even upon two-fold differences in the absolute values of rates and concentrations.
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