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  • Title: [The occurrence of proinsulin and C-peptide in healthy humans and in diabetics].
    Author: Beischer W.
    Journal: Fortschr Med; 1982 Sep 02; 100(33):1508-12. PubMed ID: 7129312.
    Abstract:
    Chemistry, biochemistry and physiology of proinsulin and C-peptide are summarized. A short characterization of the radioimmunological methods for measuring C-peptide and proinsulin follows. The determination of C-peptide and proinsulin which was mainly carried out in serum or plasma essentially improved our knowledge about the function of the beta-cells in the islets of Langerhans in healthy subjects and diabetic patients. The paper reports on the occurrence and the course of C-peptide and proinsulin in healthy subjects and in diabetics of type I and II.
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