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  • Title: Adenohypophyseal cytology of chemically and surgically thyroidectomized cockerels.
    Author: Snapir N, Robinzon B, Hoffman Y, Berman A.
    Journal: Poult Sci; 1982 Aug; 61(8):1720-8. PubMed ID: 7134126.
    Abstract:
    Reproductive traits and histology of the adenohypophysis were studied in adult White Leghorn cockerels after surgical thyroidectomy or .1% propylthiouracil (PTU) food supplementation. Both treatments caused hypothyroidism as judged by a marked reduction in plasma thyroxine levels, a decrease in resting metabolic rate values, an increase in liver and adipose tissue weights, and a marked elevation in the alcianophilic cell population in the adenohypophysis. Both the PTU-treated and thyroidectomized birds demonstrated reduced testes and comb weights. However, although thyroidectomy was found to increase the number of PAS-positive cells in the adenohypophysis, the PTU treatment reduced them. This phenomena is discussed.
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