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  • Title: The teratogenicity of cocaine.
    Author: Fantel AG, Macphail BJ.
    Journal: Teratology; 1982 Aug; 26(1):17-9. PubMed ID: 7135254.
    Abstract:
    Pregnancy rats and mice received high doses of cocaine hydrochloride by intraperitoneal injection. Despite treatment periods which included most of organogenesis, no increase in congenital abnormalities was observed. Rats showed significant reductions in maternal and fetal weights as well as increased resorption frequencies. Fetal edema was also found. Mice showed only decreased fetal weights with no increase in malformations.
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