These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Artificial sweeteners and human bladder cancer.
    Author: Howe GR, Burch JD, Miller AB, Morrison B, Gordon P, Weldon L, Chambers LW, Fodor G, Winsor GM.
    Journal: Lancet; 1977 Sep 17; 2(8038):578-81. PubMed ID: 71398.
    Abstract:
    A positive association between the use of artificial sweetners, particularly saccharin, and risk of bladder cancer in males has been observed in a case-control study of 480 men and 152 women in three Provinces in Canada. The risk ratio for ever versus never used is 1-6 for males (P=0-009, one-tailed test), and a significant dose-response relationship was obtained for both duration and frequency of use. The population attributable risk for males is estimated at 7%, though for diabetics, who have a similar risk ratio for artificial sweetner use as non-diabetics, the attributable risk is 33%.
    [Abstract] [Full Text] [Related] [New Search]