These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Response of plasma catecholamines and blood pressure to clonidine and to sudden withdrawal of the drug in subjects with essential hypertension.
    Author: Planz G, Beckenbauer U, Bundschu HD.
    Journal: Int J Clin Pharmacol Ther Toxicol; 1982 Oct; 20(10):474-8. PubMed ID: 7141755.
    Abstract:
    In this retrospective study in ten patients with essential hypertension a short-time treatment of 3 days with 0.15 mg clonidine 2 times/day orally, as well as a second short-term treatment period with the slow-release oral preparation (.025 mg clonidine once/day) significantly lowered blood pressure, heart rate, and plasma concentration of norepinephrine in the supine and standing subject. After sudden withdrawal of clonidine all these parameters returned to pretreatment levels within 2-3 days. No rebound or overshoot phenomenon was observed.
    [Abstract] [Full Text] [Related] [New Search]