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  • Title: Ferensimycins A and B. Two polyether antibiotics. Taxonomy, fermentation, isolation, characterization and structural studies.
    Author: Kusakabe Y, Mizuno T, Kawabata S, Tanji S, Seino A, Seto H, Otake N.
    Journal: J Antibiot (Tokyo); 1982 Sep; 35(9):1119-29. PubMed ID: 7142018.
    Abstract:
    Ferensimycin A* (I), C34H59O10Na, mp 133 approximately 135 degrees C, and ferensimycin B** (II), C35H61O10Na, mp 143 approximately 145 degrees C, were isolated as their sodium salts from the fermentation broth of Streptomyces sp. No. 5057, a strain similar to Streptomyces myxogenes Shomura et al. The physicochemical data of I and II showed that they are both closely related congeners of lysocellin (III). Ferensimycins A and B exhibit activity against Gram-positive bacteria and are effective in the treatment of coccidiosis of fowl.
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