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  • Title: Sister-chromatid exchange and chromosomal aberration induction in cultured Chinese hamster cells by the monomethylbenz[a]anthracenes.
    Author: Connell JR.
    Journal: Mutat Res; 1982 Sep; 102(2):173-82. PubMed ID: 7144778.
    Abstract:
    The ability of the 12 monomethylbenz[a]anthracene isomers, following their metabolism by using the cell-mediated activation system, to induce 8-azaguanine-resistant mutants, sister-chromatid exchanges (SCEs) and chromosomal aberrations has been measured. Both the mutagenic potency and the ability of the monomethylbenz[a]anthracenes to induce SCEs correlated with their carcinogenic activity. None of the monomethylbenz[a]anthracenes were particularly clastogenic.
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