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  • Title: [Direct relation between the significantly increased IgG specific antibody titer and the clinico-evolutive form in respiratory infections in infants and children. IgA and IgD levels in the evolution].
    Author: Roman S, Plavoşin L, Laky M, Buzilă L.
    Journal: Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol; 1982; 27(2):81-90. PubMed ID: 7146761.
    Abstract:
    Of 69 children suffering from acute respiratory infections, with increased IgG titers 34 presented normal or high IgAs titers in the laryngotracheal exudate. All these patients had a favourable evolution. The other children with low IgAs levels or absent IgAs in the laryngotracheal exudate had a prolonged relapsing evolution, regardless of serum IgG levels. The presence of IgA 7S in the laryngotracheal exudate did not influence the course of the disease. As a conspicuous parallelism was observed between laryngotracheal exudate IgAs and serum IgA it was assumed that IgAs participates in the formation of serum IgA "mixtures". Increased IgD values were found in 34 of these patients, ten of whom presented respiratory allergy and recurrent infections.
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