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  • Title: Effect of sulfur dioxide-sulfate exposure on rat respiratory tract clearance.
    Author: Mannix RC, Phalen RF, Kenoyer JL, Crocker TT.
    Journal: Am Ind Hyg Assoc J; 1982 Sep; 43(9):679-85. PubMed ID: 7148689.
    Abstract:
    The effects of a 4 hour exposure to a model sulfur pollutant atmosphere on the clearance of inhaled insoluble tracer particles from the lungs of rats has been studied. The pollutant combination consisted of 5 ppm of sulfur dioxide gas and 1.5 mg/m3 of sulfate aerosol at 80-85% relative humidity. The exposure atmosphere was aged for 30 minutes upstream of the exposure chamber in an aging line in order to provide for gas/ particle interactions such as those occurring in industrial and environmental atmosphere. Results indicate that the sulfur pollutant atmosphere did not produce a statistically significant alteration in early (nasopharyngeal and tracheobronchial) or late (parenchymal) clearance rates such as those which have been identified in this laboratory following exposure to ozone-containing atmospheres.
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