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Title: Metastatic retinoblastoma and L-phenylalanine mustard-dianhydrogalactitol. Author: Helson L, Kitchin FD, Abramson D, Ellsworth RM. Journal: Anticancer Res; 1982; 2(4):235-8. PubMed ID: 7149653. Abstract: Retinoblastomas heterotransplanted to nude mice were shown to be sensitive to a combination of phenylalanine mustard and dianhydrogalactitol. A patient with metastatic retinoblastoma was treated with this combination and had a significant response with complete clinical clearance of her bone marrow and metastatic tumors. However, the patient's response was similar to that observed in nude mice; recurrences of tumors developed after complete clinical remission.[Abstract] [Full Text] [Related] [New Search]