These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Acetylcholinesterase of the motor endplate and its response to muscle denervation.
    Author: Dauber W.
    Journal: Biophys Struct Mech; 1982; 9(2):117-24. PubMed ID: 7150700.
    Abstract:
    In innervated and denervated sternohyoid muscles of adult mice the AChE with a pH optimum at 7.2 was shown to occur in all three fiber types in two separate structural areas located: extrafibrillarly (synaptic cleft, postsynaptic folds, subsarcolemmal vesicles, T-tubules, interfibrillar space) and intrafibrillarly (perinuclear cisternae, SR including SR cisternae). There is not a stable connection between the two areas. The functional significance of the intrafibrillar AChE, in particular, is unknown. After muscle denervation, intrafibrillar AChE of the A and B fibers disappears more quickly than that of C fibers. This phenomenon not only suggests a general, but possibly also a fiber-specific neurotrophic effect.
    [Abstract] [Full Text] [Related] [New Search]