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  • Title: [Study of the biological activity of spleen extracts containing inhibitor of DNA-ase I].
    Author: Drozhennikov VA, Olontseva OI, Liashchenko VA, Perevezentseva OS.
    Journal: Biull Eksp Biol Med; 1982 Nov; 94(11):20-1. PubMed ID: 7150728.
    Abstract:
    Fractions of calf spleen extracts possessing the increased potency to inhibit the activity of DNase 1 were obtained by chromatography on columns with Sephadex G-200 and CM-cellulose. The fractions containing the most powerful inhibitor of DNase 1 increased the survival rate of sublethally irradiated mice and hamsters. A possible role of the DNase 1 inhibitor in cure effects is discussed.
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