These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Chondro-osseous changes in Cerebro-Oculo-Facial-Skeletal (COFS) syndrome.
    Author: Hwang WS, Trevenen CL, Greenberg C, Reed MH.
    Journal: J Pathol; 1982 Sep; 138(1):33-40. PubMed ID: 7153815.
    Abstract:
    Radiological and pathological findings were described in three cases of COFS syndrome. Early diagnosis of this syndrome is possible by the recognition radiologically of the characteristic proximal displacement of second metatarsals and pathologically by the extensive cell necrosis in the iliac crest biopsy. Pathological findings, including the presence of nuclear bodies in chondrocytes and amianthoid fibres surrounding necrotic cartilage cells, are compatible with a primary degenerative/deformative disorder. The aetiology of this syndrome is unknown.
    [Abstract] [Full Text] [Related] [New Search]