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  • Title: [Clinical use of acetylspiramycin for primary atypical pneumonia in the field of pediatrics].
    Author: Maruno H, Miyazawa W, Tahara K, Miyazaki M, Kinoshita T, Shinozuka T.
    Journal: Jpn J Antibiot; 1982 Aug; 35(8):2131-6. PubMed ID: 7154255.
    Abstract:
    Thirty-one patients with primary atypical pneumonia (16 patients diagnosed as Mycoplasma pneumonia) who visited our Department of Pediatrics between March and December, 1981 were treated with 200 mg tablets of acetylspiramycin. Clinical effects were studied, and the results were as follows. 1. Acetylspriramycin, in principle 30 mg/kg/day, was given to 31 patients with primary atypical pneumonia. The effective rate was 87.1%. (As for the patients with Mycoplasma pneumonia, the effective rate was 93.8%). 2. There was 1 ineffective case and it was judged as a case of other viral pneumonia by the results of clinical laboratory tests. 3. The only side effect observed was eruption which occurred on the 6th day of administration in 1 case and disappeared after the change of administration. From the above results, acetylspiramycin is thought to be an effective antibiotic on primary atypical pneumonia.
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