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  • Title: Fulminating pneumococcal septicaemia and meningitis in an adult twenty years after splenectomy for a ruptured spleen.
    Author: Tan KH.
    Journal: Neth J Surg; 1982 Dec; 34(5):222-4. PubMed ID: 7162682.
    Abstract:
    A nearly fatal course of pneumococcal septicaemia and meningitis in a previously healthy adult, 20 years after splenectomy for a ruptured spleen, is described. This underlines the important role of the spleen in the defence mechanism of the body against pathogenic micro-organisms. Awareness of the existence of this syndrome of overwhelming post-splenectomy infection (OPSI) is clinically important. Several aspects of prevention and treatment are discussed in a review of the literature.
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