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  • Title: Osteogenesis imperfecta 1982.
    Author: Spranger J.
    Journal: Prog Clin Biol Res; 1982; 104():223-35. PubMed ID: 7163268.
    Abstract:
    Osteogenesis imperfecta is a highly heterogeneous disorder comprising at least four major clinically discernible conditions. Clinical and genetic observations suggest further heterogeneity. Recent advances in collagen biochemistry suggest heterogeneity of clinically identical conditions and permit a tentative clinical-biochemical classification of osteogenesis imperfecta.
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