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  • Title: Management of missed abortion by intramuscular administration of 15(S) 15 methyl prostaglandin F2 alpha.
    Author: Mapa MK, Singh PM, Misra I.
    Journal: Asia Oceania J Obstet Gynaecol; 1982 Dec; 8(4):369-72. PubMed ID: 7171346.
    Abstract:
    22 subjects with a diagnosis of missed abortion were induced with 15(S) 15 methyl prostaglandin F2alpha (PGF2alpha) by the intramuscular route. The induction succeeded in all cases. The mean induction-abortion interval was 16 hours with a range of 2 hours 30 minutes to 32 hours 10 minutes. The average dose of 15 methyl PGF2alpha required was 1675 mcg. 9 subjects (42%) had complete abortions. 7 (31.8%) had no gastrointestinal side effects. The mean number of episodes of vomiting and diarrhea was 1.3 and 0.8 respectively. 15(S) 15 methyl PGF2alpha has a high degree of efficacy in the management of missed abortion.
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