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  • Title: Base-pair formation between 18 S ribosomal RNA and globin mRNA during initiation of protein synthesis in vitro.
    Author: Erni B, Staehelin T.
    Journal: FEBS Lett; 1982 Nov 01; 148(1):79-82. PubMed ID: 7173403.
    Abstract:
    A stable complex between 18 S rRNA and globin mRNA has been isolated from 40 S initiation complexes in the reconstituted reticulocyte cell free system. This complex is only formed under the conditions which also lead to an initiation complex active in protein synthesis. The mRNA-18 S rRNA interaction has properties compatible with base-pairing. This observation is discussed in the context with other, in part controversial, observations relating to base pairing as a step in initiation of eukaryotic protein synthesis.
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