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  • Title: [Serum lipoproteins in chronic alcoholics. Changes in HDL, VLDL and LDL as a function of the degree of hepatic involvement].
    Author: Peynet J, Legrand A, Techenet P, Isal JP, Guillausseau PJ, Rousselet F.
    Journal: Nouv Presse Med; 1982 Oct 30; 11(43):3179-83. PubMed ID: 7177834.
    Abstract:
    Changes in lipoprotein fractions HDL and LDL-VLDL were investigated in 84 chronic alcoholic patients and attempts were made to correlate these changes with the severity of liver damage. In 40 patients with undetectable hepatic lesions the lipoprotein fractions were not reduced but a rapidly reversible increase in HDL was noted in 15%. The 14 patients with steatosis and alcoholic hepatitis showed a fall in HDL, often associated with an increase in plasma triglycerides; these changes regressed during weaning. The 30 patients with cirrhosis of the liver had irreversibly low HDL and LDL levels.
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