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  • Title: Some improvements in the separation technique for the chemical syntheses of oligodeoxyribonucleotides.
    Author: Tanaka H, Muraki M, Honda K, Nakazato S.
    Journal: Nucleic Acids Symp Ser; 1982; (11):73-6. PubMed ID: 7183974.
    Abstract:
    Some improvements have been achieved for the separation technique in the syntheses of oligodeoxyribonucleotides by a solid phase phosphotriester method; (1) reuse of the protected nucleotides recovered from the reaction mixture by a preparative GPC. (2) a new weak anion exchange column, HPLC-DEAE, was used to estimate the size of the deblocked oligomers.
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