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  • Title: [Precancerous lesions associated with atrophic chronic gastritis and gastric peptic ulcer].
    Author: Nogueira AM, Barbosa CS, Miranda D.
    Journal: Arq Gastroenterol; 1982; 19(4):169-74. PubMed ID: 7186401.
    Abstract:
    Among the gastric lesions related to an increased risk for gastric cancer (precancerous conditions) two have deserved special attention, i.e., atrophic gastritis and peptic ulcer. In this paper the authors study the incidence of glandular dysplasia in atrophic gastritis and gastric peptic ulcer. In 148 cases of atrophic gastritis dysplastic lesions were diagnosed in 92 (62,0%): 63 cases (68,4%) with mild dysplasia, 25 cases (27,0%) with moderate dysplasia and 4 cases (4,3%) with severe dysplasia. In 329 gastric peptic ulcers examined there were 51 (15,5%) with dysplastic lesions: in 34 cases (66,6%) there was mild dysplasia, 12 cases (23,5%) moderate dysplasia and (9,8%) severe dysplasia. A prospective study with histological multiple sections from the stomach would be helpful for better understanding of these precancerous lesions.
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