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  • Title: Endogenous GABA release from slices of rat cerebral cortex and hippocampus in vitro.
    Author: Fan SG, Lee CM, Assaf SY, Iversen LL.
    Journal: Brain Res; 1982 Mar 11; 235(2):265-70. PubMed ID: 7188328.
    Abstract:
    Using a rapid, simple and sensitive radioreceptor assay, a Ca2+-dependent K+-evoked release of endogenous GABA was demonstrated from rat cortical and hippocampal slices in vitro. This evoked-release of endogenous GABA was similar to that of [3H]GABA release (in its Ca2+ dependency) but differed from the latter in having a higher signal to noise level. Neither 5-HT nor a stable enkephalin analogue had any effect on endogenous GABA release from hippocampus slices.
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