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  • Title: Detection of thymoma in myasthenia gravis.
    Author: Keesey J, Bein M, Mink J, Sample F, Sarti D, Mulder D, Herrmann C, Peter JB.
    Journal: Neurology; 1980 Mar; 30(3):233-9. PubMed ID: 7189022.
    Abstract:
    Twenty patients with myasthenia gravis had chest radiography, conventional tomography, and computed tomography (CT) of the thorax within 1 month of thymectomy. Four of the six macroscopic tumors were detected on routine chest radiography; conventional tomography provided no additional information. CT detected all six macroscopic tumors and provided additional information that was not available by other procedures. However, 18 patients (90%) had anterior mediastinum densities on CT, which could not be distinguished preoperatively from thymic tumors. All six patients with macroscopic tumors had serum antistriational muscle antibody titers; this test was negative in 10 of 11 patients (91%) without thymoma. Chest radiography, CT of the thorax, and antistriational antibodies are the tests recommended for detection of a thymoma in patients with myasthenia gravis.
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