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  • Title: Pregnancy complicated by the Kasabach-Merritt syndrome.
    Author: Phillippe M, Acker D, Frigoletto FD.
    Journal: Obstet Gynecol; 1980 Aug; 56(2):256-8. PubMed ID: 7190257.
    Abstract:
    The Kasabach-Merritt syndrome is the association of cavernous hemangiomas and consumption coagulopathy marked by anemia, thrombocytopenia, and hypofibronigenemia. Exacerbation of the consumption coagulopathy has been described in the 2 previous reports of this syndrome when associated with pregnancy. The authors report a third patient whose delivery and postopartum course were marked by increased coagulation abnormalities and subsequent hemorrhage. This patient's 32-day hospital course and need for multiple blood transfusions, clotting factors, platelets, heparin, and finally epsilon-aminocaproic acid underscore the need for patients with this syndrome to deliver in a referral center hospital where replacement therapy and hematologic consultation are readily available.
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