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  • Title: [Comparison of the frequency of chromosomal disorders in populations of in vitro-matured and ovulating rat oocytes].
    Author: Kitaev EM, Pimenova MN.
    Journal: Biull Eksp Biol Med; 1980 Dec; 90(12):721-3. PubMed ID: 7193494.
    Abstract:
    The rat oocytes extracted from the rat ovaries and cultivated for 42-46 hours were compared with ovulated oocytes by the chromosomal aberration rate. The chromosomal aberration rate in the population of "follicular" oocytes was 8.2% on the average whereas in ovulated oocytes, it did not exceed 1.8%. Analysis of the chromosomal aberrations depending on the phase of the estral cycle suggests that the main portion of chromosomal aberrations in cultivated oocytes occurs during the physiological process of follicular atresia.
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