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  • Title: Hypertrophic cardiomyopathy in Friedreich's ataxia: symmetric or asymmetric?
    Author: Pasternac A, Król R, Petitclerc R, Harvey C, Andermann E, Barbeau A.
    Journal: Can J Neurol Sci; 1980 Nov; 7(4):379-82. PubMed ID: 7194134.
    Abstract:
    We evaluated 15 patients with Friedreich's ataxia (FA) to define the incidence of myocardial involvement and the type of cardiomyopathy observed. All patients with FA had either ECG, vectocardiographic or echocardiographic abnormalities, suggesting some degree of myocardial involvement. In contrast to reports indicating that asymmetric septal hypertrophy (ASH), often obstructive, is associated with FA, symmetric, concentric hypertrophic cardiomyopathy (SCH) was the predominant abnormality (sixty-seven percent of patients). Echocardiograms should be performed periodically in all FA patients since this technique allows the detection of cardiac hypertrophy.
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