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Title: Borderline tuberculoid leprosy following BCG vaccination. A case report. Author: Stoner GL, Belehu A, Nsibambi J, Warndorff J. Journal: Int J Lepr Other Mycobact Dis; 1981 Mar; 49(1):16-20. PubMed ID: 7195879. Abstract: Borderline tuberculoid leprosy was diagnosed clinically and histologically in a four year-old boy about 6 months after intradermal vaccination with BCG. His mother reported that a lesion began to appear above the vaccination site on the arm 2 weeks after the vaccination, and a second lesion appeared on the chin 2 months later. Responses in the lymphocyte transformation test to sonicated Mycobacterium leprae, BCG, and to PPD were consistent with a tuberculoid leprosy infection. Precipitation of BT leprosy by intradermal BCG infection may possibly represent the overcoming of a phase of primary suppression in an individual who might otherwise have progressed toward lepromatous leprosy. The implications of this hypothesis for the planning of a controlled trial of an anti-leprosy vaccine are discussed.[Abstract] [Full Text] [Related] [New Search]