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  • Title: Serotonin concentrations in brain and blood of scrapie-infected and normal hamsters and mice.
    Author: Rohwer RG, Neckers LM, Trepel JB, Gajdusek DC, Wyatt RJ.
    Journal: Brain Res; 1981 Sep 14; 220(2):367-71. PubMed ID: 7197184.
    Abstract:
    Whole brains and bloods of scrapie-infected and control mice and hamsters were assayed for serotonin content. Late clinical scrapie-infected mice showed a 20% reduction in whole-brain serotonin concentrations but no change in blood concentrations relative to controls. Late clinical scrapie-infected hamsters showed no change in whole-brain serotonin concentrations but a 2.5-fold decrease in blood concentrations relative to controls.
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