These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Ointments for the protection against organophosphate poisoning.
    Author: Reiner R, Rossmann K, van Hooidonk C, Ceulen BI, Bock J.
    Journal: Arzneimittelforschung; 1982; 32(6):630-3. PubMed ID: 7202369.
    Abstract:
    Ointments for the protection against poisoning of the skin by highly toxic organophosphates or organophosphate insecticides were prepared and examined for their protective effect both on guinea-pig skin in vitro and on guinea-pigs in vivo. The results of these investigations were as follows: 1. The prophylactic application of the ointments yields 20 fold reduction of the permeation rate of the toxic organophosphate compared with unprotected skin. 2. The ointments on a polyethyleneglycol basis show their best protective effect if they contain both a base and an active substance. 3. Maximum possible protection can be achieved by applying a thick layer of ointment which should be mechanically removed (by wiping with a damp cellulose tissue) from the contamination site within 30 min.
    [Abstract] [Full Text] [Related] [New Search]