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  • Title: Human platelet stimulation by acetyl glyceryl ether phosphorylcholine.
    Author: McManus LM, Hanahan DJ, Pinckard RN.
    Journal: J Clin Invest; 1981 Mar; 67(3):903-6. PubMed ID: 7204562.
    Abstract:
    Acetyl glyceryl ether phosphorylcholine (AGEPC) induced dose-dependent platelet aggregation and release of [3H]serotonin and platelet factor 4 in citrated human platelet-rich plasma. ADP scavengers or indomethacin prevented irreversible platelet aggregation responses induced by 0.2 microM AGEPC but had no effect upon platelet secretion; prostacyclin inhibited AGEPC-induced aggregation and secretion. EDTA or EGTA inhibited AGEPC-induced aggregation but had no effect on platelet secretion.
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