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  • Title: Rapid intracerebroventricular injection assisted by an automatic syringe.
    Author: Lipman JJ, Spencer PS.
    Journal: J Pharmacol Methods; 1980 Dec; 4(4):327-33. PubMed ID: 7206740.
    Abstract:
    Rapid intracerebroventricular (icv) injections in the conscious mouse are described, using a small volume gas-tight syringe with repeating dispenser device (Hamilton Bonadoz, Switzerland). The device gives reproducibility within 2% of chosen volume, while facilitating rapid icv injections to groups of animals. The technique is used to demonstrate in the mouse the antinociceptive activity of clonidine, using the tail-immersion test.
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