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  • Title: Granulocytopenia with marked lymphocytosis manifesting Sjogren syndrome.
    Author: Goske J, Askari AD, Dickman E, Forman WB, Crum ED.
    Journal: Am J Hematol; 1980; 9(4):435-7. PubMed ID: 7211836.
    Abstract:
    Sjogren syndrome is a multi-system disease leading to diverse organ involvement during its course [1, 2]. Hematologic abnormalities described in Sjogren syndrome include anemia, mild leukopenia [3, 4], eosinophilia, elevated erythrocyte sedimentation rate, hypergammaglobulinemia, mixed cryoglobulinemia, and a variety of autoantibodies [5]. Marked lymphocytosis with granulocytopenia is distinctly unusual and has not been previously reported. We report a case of Sjogren syndrome who presented with constellation of the latter problems without prominent sicca manifestations.
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