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  • Title: Effect of administration of isatin on alkaline phosphatase of various organs of rat.
    Author: Singh B, Kumar P, Nagpaul JP, Sharma R, Bansal RC.
    Journal: Indian J Physiol Pharmacol; 1978; 22(3):297-300. PubMed ID: 721252.
    Abstract:
    In vivo administration of isatin (200 mg/kg) significantly lowered the activity of rat kidney alkaline phosphatase after 5 hr but enhanced the activity of rat duodenal and jejunal enzyme after 2 and 5 hr (P less than 0.01). The increased activity of the duodenal and jejunal alkaline phosphatase might be due to the induction of the enzyme by isatin.
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