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Title: Anti-pigment-cell factors and mucocutaneous candidiasis. Author: Nordlund JJ, Howanitz N, Bystryn JC, Forget BM, Lerner AB. Journal: Arch Dermatol; 1981 Apr; 117(4):210-2. PubMed ID: 7212742. Abstract: Previous reports documented the fact that some patients with mucocutaneous candidiasis and vitiligo have a complement-fixing anti-pigment-cell factor in their serum. We examined sera from seven patients with mucocutaneous candidiasis without vitiligo. Three of the seven sera contained the anti-pigment-cell factor. We suggest that these anti-pigment-cell factors, which are most probably antibodies, are not cytotoxic for pigment cells and, thus, not the cause of vitiligo. The association of vitiligo and anti-pigment-cell factors with the syndrome of mucocutaneous candidiasis implicates the immune system are a causal factor of vitiligo.[Abstract] [Full Text] [Related] [New Search]