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  • Title: Electron microscopic demonstration of adenylate cyclase activity in rat cortical synaptosomes.
    Author: Rostomian MA, Abramian KS, Hajós F.
    Journal: Histochemistry; 1981; 70(2):167-71. PubMed ID: 7216833.
    Abstract:
    The electron cytochemical demonstration of adenylate cyclase activity was carried out in rat cortical synaptosomes. Reaction product was found in 60-70% of the synaptosomes in three predominant localization: (i) on the postsynaptic density; (ii) on the outer aspect of the synaptosomal membrane; (iii) inside the synaptosome. Results suggest that in addition to postsynaptic localization adenylate cyclase activity is cytochemically demonstrable also at presynaptic sites.
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