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  • Title: Kinetics of IgM and IgG responses in neonatally thymectomized Swiss mice under persistent immunization with sheep red blood cells.
    Author: Gras J, Silva M, Castro MR, Vives J.
    Journal: Rev Esp Fisiol; 1980 Dec; 36(4):399-402. PubMed ID: 7221162.
    Abstract:
    The kinetics of IgM and IgG responses (direct and indirect PCF) in the Swiss mice, neonatally thymectomized, injected three times a week with 5 X 10(8) sheep erythrocytes at the age of two months, were exactly the same as the controls from the same litters. The thymectomized animals showed a statistically significant decrease in both responses (18.6 and 30.2%, respectively). The kinetics of the switch from IgM to IgG and of the latter response inhibition, is the same in both the control and the thymectomized animals.
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