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  • Title: In-111 transferrin labeling studied by perturbed angular correlations.
    Author: Martin PW, Skov K.
    Journal: J Nucl Med; 1978 Oct; 19(10):1171-4. PubMed ID: 722329.
    Abstract:
    The technique of perturbed angular correlations (P.A.C.) was used to study transferrin labeled with radioactive indium. Three forms of the labeled system were studied: a) the In-111 was bound to transferrin with no iron present at either of the binding sites; b) the In-111 probe was used to label transferrin that was 33% saturated with iron; and c) the label was attached to saturated Fe-transferrin. The measured perturbation factors, G22(t), indicate that the three binding states are clearly differentiated. Cases (a) and (b) exhibit characteristic features of time-independent quadrupole interactions and the average quadrupole interaction frequencies, omegaq, were determined in these cases.
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