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  • Title: [Droperidol-ketamine. Clinical studies of an intravenous anaesthesia for peripheral operations on children (author's transl)].
    Author: Breucking E, Altemeyer KH, Dick W.
    Journal: Anaesthesist; 1981 Mar; 30(3):107-10. PubMed ID: 7224139.
    Abstract:
    Children aged 4 to 13 years who underwent small surgical operations, received anaesthesia with an intravenous injection of droperidol and ketamine. The children breathed spontaneously. The first group breathed room air only, the second group were given air enriched with oxygen at 21 per min. Five, 15, 25, and 35 minutes after the first injection we made the following measurements: pulse rate, arterial blood pressure, respiratory minute volume and frequency, and arterial blood gases. Arterial pCO2 values remained within the normal range. Arterial pO2 values showed a broad variation from 68 to 162 mm Hg. In the first group 25% of values lay between 68 and 75 mm Hg, where oxygen saturation is still sufficient but the oxygen dissociation curve steepens. In the second group with a higher inspiratory oxygen concentration we never found values below 75 mm Hg. As a result of these investigations we can say that this intravenous combination anaesthesia can be recommended for peripheral operations of short duration if an increased inspiratory oxygen concentration under spontaneous breathing is used.
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