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  • Title: A swine dysentery model for evaluation of drug prophylaxis: efficacy of various drugs in the control of swine dysentery.
    Author: Raynaud JP, Brunault G, Patterson EB.
    Journal: Am J Vet Res; 1981 Jan; 42(1):51-3. PubMed ID: 7224318.
    Abstract:
    A swine dysentery (SD) model that produces consistent, homogeneous, and severe SD was used in 2 experiments to compare the prophylactic effectiveness of 5 commercially available swine feed additive products. Under the conditions of these studies, carbadox and carbadox + sulfamethazine proved to be the most effective agents in preventing SD during the infection + medication and postmedication periods. Olaquindox was effective in preventing SD in the infection + medication period; however, SD recurrence was high during the postmedication period. Nithiamide and chlortetracycline + sulfamethazine + penicillin were least effective in preventing SD during the infection + medication and postmedication periods.
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