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  • Title: Presynaptic calcium currents in squid giant synapse.
    Author: Llinás R, Steinberg IZ, Walton K.
    Journal: Biophys J; 1981 Mar; 33(3):289-321. PubMed ID: 7225510.
    Abstract:
    A voltage clamp study has been performed in the presynaptic terminal of the squid stellate ganglion. After blockage of the voltage-dependent sodium and potassium conductances, an inward calcium current is demonstrated. Given a step-depolarization pulse, this voltage- and time-dependent conductance has an S-shaped onset. At the "break" of the voltage step, a rapid tail current is observed. From these results a kinetic model is generated which accounts for the experimental results and predicts for the time course and amplitude a possible calcium entry during presynaptic action potentials.
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