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  • Title: Bone formation and impedance of electrical current flow.
    Author: Collins PC, Paterson DC, Vernon-Roberts B, Pfeiffer D.
    Journal: Clin Orthop Relat Res; 1981; (155):196-210. PubMed ID: 7226614.
    Abstract:
    The impedance to current flow to an electrically stimulated cathode did not change appreciably over a 12-week measurement period and did not support the hypothesis of a temporal relationship between bone formation and impedance to current flow in the region of the cathode. The use of an electrically stimulated titanium cathode at a current density of 0.33 microA/mm2 in this model of canine delayed union resulted in a significant bone formation when analyzed by quantitative and qualitative methods. Sequential quantitative radionuclide scanning correlated well with histologic appearance of bone formation and was a sensitive indicator of electrically induced osteogenesis.
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