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  • Title: Steroid receptors in adjuvant hormonal therapy for breast cancer.
    Author: Goldie JH, Bruchovsky N, Coldman AJ, Gudauskas GA.
    Journal: Can J Surg; 1981 May; 24(3):290-3. PubMed ID: 7237303.
    Abstract:
    Using a computerized mathematical model the authors found that either a small [5%] or large [50%] hormone-dependent reduction in tumour cell population at the beginning of adjuvant chemotherapy for breast cancer greatly increases the probability fo achieving a cure. The fact that even a minor response to hormonal therapy early in the treatment of the tumor is effective underlines the importance of using estrogen receptors to to select potential responders in whom a cure is at least a strong theoretical possibility.
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