These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Adsorption of oral antidotes for acetaminophen poisoning (methionine and n-acetylcysteine) by activated charcoal.
    Author: Klein-Schwartz W, Oderda GM.
    Journal: Clin Toxicol; 1981 Mar; 18(3):283-90. PubMed ID: 7237961.
    Abstract:
    An in vitro experiment was performed to assess the degree of adsorption of oral antidotes for acetaminophen poisoning, methionine and N-acetylcysteine, by activated charcoal. Results indicate that activated charcoal effectively adsorbs both methionine and N-acetylcysteine. Since these agents must be absorbed from the GI tract to prevent acetaminophen hepatotoxicity, concurrent administration of methionine or N-acetylcysteine and activated charcoal would be expected to markedly diminish their antidotal effectiveness.
    [Abstract] [Full Text] [Related] [New Search]