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  • Title: [Treatment of agammaglobulinemia in the adult; report of 9 cases].
    Author: Guignot B, Arnaud P, Ezra P, Emonot A, Brune J, Galy P.
    Journal: Poumon Coeur; 1977; 33(4):235-41. PubMed ID: 72386.
    Abstract:
    The study of 9 cases of agammaglobulinemia in the adult shows the classical symptomatology of these diseases. The evolutive study deals with too small a series to demonstrate statistically the superiority of the substitutive treatment over a simple chemo-therapeutic prevention of the infection, but nevertheless it shows : 1) that prognosis is bad only in cases of gross anatomical and physiological alterations and when they are the sole responsible for a fatal evolution; 2) that the substitutive treatment is only really efficient when given at high doses; the minimum dose of 250 mg per day seems advisable.
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