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  • Title: [New esters of substituted anilinonicotinic and phenylanthranilic acids].
    Author: Los M, Boned JE, Piccinali C.
    Journal: Farmaco Sci; 1981 May; 36(5):372-85. PubMed ID: 7238853.
    Abstract:
    In the search for new non-steroidal antiinflammatory drugs with low ulcerogenic activity, phthalidyl and pivaloyloxymethyl esters of anilinonicotinic and N-phenylanthranilic acids were synthesized. One of them, the 3-phthalidyl ester of 2-([3-(trifluoromethyl)phenyl]amino)-3-pyridinecarboxylic acid, also named talniflumate, showed lower ulcerogenic activity and toxicity and greater antiinflammatory activity than the niflumic acid.
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