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  • Title: [Substances with antiviral activity. XX. Thiosemicarbazones of 1-substituted 3-formyl-2-ethoxycarbonyl(carboxy)indoles].
    Author: Giovanninetti G, Garuti L, Cavrini V, Gatti R, Mannini Palenzona A, Baserga M.
    Journal: Farmaco Sci; 1981 May; 36(5):386-92. PubMed ID: 7238854.
    Abstract:
    A series of 3-formyl-2-ethoxycarbonyl(carboxy)indole thiosemicarbazones 1-substituted were synthesized and evaluated for in vitro antiviral activity against vaccinia virus strain IHD. The thiosemicarbazone of 1-(m-chlorobenzoyl)-3-formyl-2-ethoxycarbonylindole [(II g); Table II] was the most active compound. Some structure activity relationships are discussed.
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