These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: Chlorpropamide-induced Syndrome of Inappropriate Antidiuretic Hormone Secretion.
    Author: Tanay A, Firemann Z, Yust I, Abramov AL.
    Journal: J Am Geriatr Soc; 1981 Jul; 29(7):334-6. PubMed ID: 7240625.
    Abstract:
    The Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) is a rare but serious complication of chlorpropamide therapy. In 2 elderly women who had diabetes mellitus, the SIADH developed two months after the chlorpropamide dosage had been increased to 500 mg daily. The syndrome disappeared after withdrawal of the drug. In one of these patients, re-administration of chlorpropamide resulted in recurrence of the SIADH. A review of the current literature disclosed certain common denominators, i.e., most of the patients are elderly women whose dosage of chlorpropamide was increased shortly before the development of the SIADH.
    [Abstract] [Full Text] [Related] [New Search]